Events

Machine-learning-based prediction of tumor multiplicity in hereditary pheochromocytoma

Dr Reut Halperin presented our work on machine-learning-based prediction of genetic alterations and multiple lesions in sporadic and hereditary pheochromocytoma and paraganglioma at the annual European Congress of Endocrinology, in Copenhagen, Denmark ON mAY 2025.

Prof Tirosh received the Hans Lindner Award

Prof Tirosh received the highest award of the 2025 Israeli Endocrine Society (IES) during its annual scientific meeting for his scientific achievements. In his prize talk, Prof Tirosh described the research conducted in the ENTIRE Center, and our future goals to continue conducting excellent translational research, focusing on neuroendocrine neoplasms and hereditary syndromes associated with these rare cancers.

The International Scientific VHL Meeting - Milan, Italy, 2024.

Prof Amit Tirosh and Dr Reut Halperin were invited to speak during the biennial Scientific Meeting of the VHL Alliance. We presented our work on VHL genetic alterations and cardiovascular and metabolic risk as part of a public, multidisciplinary team discussion on the management of patients with VHL, and Ms Yuval Kahan Yossef from our research lab presented on drivers of progression of VHL-related pancreatic neuroendocrine tumors.

ENTIRE Traveling Clinic

To bridge the distance gap for patients with hereditary syndromes from remote locations in Israel, we initiated our Traveling Clinic. Since 2021, we have conducted our expert clinic outside the Sheba MC every 3-4 months. In the clinic, we perform a thorough evaluation, including genetic testing for patients from high-risk families.

The 1st Traveling Clinic focused on families with VHL, evaluating more than 10 patients, diagnosing new patients with VHL, and identifying urgent manifestations in newly diagnosed patients.

2022

Our team continues to fulfill our goal of being available to everyone, everywhere: we conducted two additional traveling clinics for patients with hereditary endocrine cancer syndromes. Our clinic reached the far northeastern and western Galilee, as well as additional locations on the Carmel mountain and other sites.

If you know of family members with neuroendocrine tumors, paragangliomas, pheochromocytoma, MEN syndrome, or VHL, please get in touch with us, and we will be at your service for advice, assessment, and/or evaluation.

To continue performing our free-of-charge genetic testing, we ask for your support. If you are interested, or know anyone who is, please let us know HERE

2021

VHL Patients Meeting
MEN1 Patients Meeting

2020

The 1st International School for MEN Syndromes

A unique school, gathering experts from all around the globe, to discuss and learn about
The management of multiple endocrine neoplasia syndromes (MEN1, MEN2, VHL, and SDHx).

2019

Excellence through synergy - Specialty-based approach to the management of VHL Disease
VHL Patients Meeting
NET 1st Service - Everything you wanted to know about neuroendocrine tumors

2018

Diarrhea in patients with gastroenteropanceratic NET - beyond the obvious